By George M. Rodgers
This finished quantity discusses the protease ADAMTS13, summarizing the present prestige of uncomplicated and scientific learn. The 9 authoritative chapters commence with a old point of view by way of exploration of the biochemistry and structure-function relationships of ADAMTS13 in addition to its general functionality in hemostasis (cleavage of von Willebrand factor). rising study issues for ADAMTS13 are coated, together with its strength function in angiogenesis and different features of cellphone biology. extra subject matters comprise laboratory assays for ADAMTS13, inherited ADAMTS13 deficiency, and bought ADAMTS13 deficiency. A bankruptcy on comparable thrombotic microangiopathic (TMA) issues examines the diversities among TMAs linked to ADAMTS13 deficiency and people no longer linked to ADAMTS13 deficiency. a last bankruptcy experiences the initial info on rising elements of ADAMTS13, akin to the prestige of recombinant ADAMTS13 items and their power utility.
Comprehensive in its exploration of the ADAMTS13 protease in disease, ADAMTS13: Biology and disorder is an important source for medical hematologists, transfusion medication physicians, and researchers attracted to hemostasis, vascular biology, biochemistry, and metalloproteases.
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Additional resources for ADAMTS13: Biology and Disease
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